The film contains five stories set on desolate stretches of a desert highway. Two men on the run from their past, a band on its way to a gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation are forced to confront their worst fears and darkest secrets in these interwoven tales.
A sociopath prone to ultra-violent fantasies attempts to transform his reclusive lifestyle when the woman of his dreams moves-in next door - with horrific consequences.
An anonymous advice columnist finds herself caught in an unlikely romance with the man who has been hired to kill her alter ego.
In the future, medical technology has advanced to the point where people can buy artificial organs to extend their lives. But if they default on payments, an organization known as the Union sends agents to repossess the organs. Remy is one of the best agents in the business, but when he becomes the recipient of an artificial heart, he finds himself in the same dire straits as his many victims.
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