After studying in Paris, the young doctor François moves to Beauval, where single-family houses are lined up monotonously. He quickly becomes the focus of a group of young people, led by the charismatic Cédric and Matthieu, his assistant. The gang tries to escape their boredom with dangerous games at the edge of the forest. But things become bitterly serious when the body of a twelve-year-old girl is found and François is suspected.
After nearly two decades of legendary criminal feats, making him France's most notorious criminal while simultaneously feeding his desire for media attention and public adoration, Mesrine becomes increasingly paranoid and isolated, leading to a dramatic confrontation with the law that ultimately seals his fate as the nation's most infamous public enemy.
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